The Guettler Lab

Divisions of Structural Biology and Cancer Biology

The Institute of Cancer Research

Publications

Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.

Mariotti L, Templeton CM, Ranes M, Paracuellos P, Cronin N, Beuron F, Morris E, Guettler S

Molecular Cell, 2016, 63 (3), 498-513

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AXIN Shapes Tankyrase ARChitecture.

Guettler S

Structure (London, England : 1993), 2016, 24 (10), 1625-1627

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The genomic landscape of oesophagogastric junctional adenocarcinoma.

Chong IY, Cunningham D, Barber LJ, Campbell J, Chen L, Kozarewa I, Fenwick K, Assiotis I, Guettler S, Garcia-Murillas I, Awan S, Lambros M, Starling N, Wotherspoon A, Stamp G, Gonzalez-de-Castro D, Benson M, Chau I, Hulkki S, Nohadani M, Eltahir Z, Lemnrau A, Orr N, Rao S, Lord CJ, Ashworth A

The Journal of Pathology, 2013, 231 (3), 301-10

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Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.

Guettler S, LaRose J, Petsalaki E, Gish G, Scotter A, Pawson T, Rottapel R, Sicheri F

Cell, 2011, 147 (6), 1340-54

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