The Guettler Lab

Divisions of Structural Biology and Cancer Biology

The Institute of Cancer Research

Current Lab

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Nisha Pillay

Nisha Pillay, BA, PhD

Postdoctoral Fellow

Location: 237 Fulham Road, London, SW3 6JB
Office Phone: +44 (0)20 7153 5212
Lab Phone: +44 (0)20 7153 5180
Email: nisha.pillay[at]

I studied Natural Sciences at the University of Cambridge majoring in Biochemistry. I then moved on to the University of Manchester to undertake a Wellcome-funded PhD in the lab of Professor Stephen Taylor investigating the poly(ADP-ribose) reversal enzyme poly(ADP-ribose) glycohydrolase (PARG) as a therapeutic target. In 2020, I joined Sebastian’s lab to pursue my interests in ADP-ribosylation biology, investigating ADP-ribosylation of tankyrase targets, with a particular interest in telomeric functions of tankyrase.


DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors.

Pillay N, Tighe A, Nelson L, Littler S, Coulson-Gilmer C, Bah N, Golder A, Bakker B, Spierings DCJ, James DI, Smith KM, Jordan AM, Morgan RD, Ogilvie DJ, Foijer F, Jackson DA, Taylor SS

Cancer Cell, 2019, 35 (3), 519-533.e8

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