Cryo-EM reveals structural basis of tankyrase activation by polymerisation
In our latest paper, we report structure-function studies that reveal how tankyrase is turned from a sluggish to an active protein by filamentous polymerisation. You can read the open-access paper here. The paper comes with a press release by ICR. Congratulations to the team!
We welcome Shafayat Azad to our team. Shaf joins us as a PhD Student and will investigate the mechanisms of telomere maintenance.
Michael speaks at “Black in Cancer”
Michael Ranes speaks at the inaugural “Black in Cancer” conference – an international collaboration between Black in Cancer and Cancer Research UK, one of our major funders.
Team Member Yexin Xie receives her PhD
Last month, we celebrated Yexin’s PhD graduation. Many congratulations Yexin on your well-deserved PhD, and all the best for your next steps!
Thank you and goodbye to Nisha!
After almost three years in the lab, Nisha is moving on. We say thank you and goodbye – all the best for the future! Stay tuned for exciting publication news coming soon.
We say thank you and farewell to Euan Colaco Osorio, who joined us for almost two months as a Summer Student funded by the Lister Institute. All the best for your next adventure!
Iona awarded poster prize at American Chemical Society Medicinal Chemistry Symposium
PhD Student Iona Black has has been awarded the Best Poster prize at the 37th American Chemical Society Medicinal Chemistry Symposium held in New York City in June 2022. To attend the conference, Iona received a Royal Society of Chemistry researcher development grant of £500. Many congratulations Iona!
2022 Lab Retreat in Hastings
Our first lab retreat in a long time: two days of science and sunshine … and lots of food.
Destruction complex reconstitution among ten featured ICR achievements of 2021
Our reconstitution of the beta-catenin destruction complex made it to ICR’s ten featured scientific achievements of 2021. What a nice way to end the lab year and a real testament to the team’s work! You can find all research highlights on the ICR website.
#BlackinCancer: Reaching communities most affected by prostate cancer
For Black in Cancer Week, ICR’s Science Communications Officer Juanita Bawagan spoke to our team member Dr Michael Ranes about the importance of diversity in cancer research for science and society. You can read the article here.